Sperm tail agenesis in a case of consanguinity.

OBJECTIVE

To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.

DESIGN

Case report.

SETTING

University-based andrology clinic.

PATIENT(S): A 27-year-old man undergoing infertility evaluation.

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.

RESULT(S): One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.

CONCLUSION(S): A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.