Department of Zoology, University of Calcutta, Calcutta, India.
Fertil Steril. 2010 May 1;93(7):2247-54. doi: 10.1016/j.fertnstert.2009.01.135. Epub 2009 Mar 27.
To compare the semen quality and age-specific changes in men between the 1980s and 2000s.
Prospective study.
Andrology laboratory, University of Calcutta, India.
PATIENT(S): A semen sample was obtained from 3729 men presenting for infertility problems in two distinct decades, that is, between 1981-85 and 2000-2006.
INTERVENTION(S): Subjects with sperm count >20 x 10(6)/mL without any extreme pathological disorders were selected. Samples having a major liquefaction problem were excluded.
MAIN OUTCOME MEASURE(S): A standard World Health Organization procedure for semen analysis was performed that included assessment of volume, sperm concentration, and percentage motility. The motility parameters were further classified into forward progressive motility and nonprogressive motility.
RESULT(S): The present large-scale study confirms a significant decline in the sperm motility parameters and seminal volume in the present decade. However, no change in overall sperm concentration was noted. A decline was seen in sperm motility with increasing age in both decades.
CONCLUSION(S): There are significant changes in sperm motility and volume between the two decades, and the age-related changes in semen parameters are also different in the two decades.
比较 20 世纪 80 年代和 21 世纪 00 年代男性的精液质量和年龄特异性变化。
前瞻性研究。
印度加尔各答大学男科实验室。
从 1981-85 年和 2000-2006 年两个不同十年间因不孕问题就诊的 3729 名男性中获得一份精液样本。
选择精子计数>20 x 10(6)/mL 且无任何极端病理障碍的受试者。排除有主要液化问题的样本。
采用世界卫生组织精液分析标准程序，包括评估体积、精子浓度和百分比活力。将运动参数进一步分为前向运动性和非运动性。
本大规模研究证实，目前这十年的精子运动参数和精液量显著下降。然而，总体精子浓度没有变化。两个十年中，精子活力随年龄的增长而下降。
两个十年之间的精子活力和体积存在显著变化，两个十年的精液参数的年龄相关变化也不同。
