Skolarikos A, Thorpe A C, Neal D E
Second Department of Urology, University of Athens, Sismanoglio Hospital, Athens, Greece.
Minerva Urol Nefrol. 2004 Jun;56(2):109-22.
Benign prostatic hyperplasia (BPH) is an important cause of lower urinary tract symptoms (LUTS). However, many other causes, including smooth muscle dysfunction and neurological factors may contribute to these symptoms, and accurate diagnosis is imperative before invasive treatments are chosen. Careful recording of symptoms, giving emphasis on how they interfere with the patient's quality of life, as well as the use of properly selected tests, constitutes the mainstay of making a correct diagnosis. Men with mild or moderate symptoms not experiencing complications are ideal candidates for medical treatment. For the rest with persistent symptoms or complications such as infection, bleeding, chronic retention or renal impairment further investigation and more invasive forms of treatment need to be considered. We review the patho-physiology of the disease, and current approaches and management of this common problem.
良性前列腺增生(BPH)是下尿路症状(LUTS)的一个重要原因。然而,许多其他原因,包括平滑肌功能障碍和神经因素,也可能导致这些症状,因此在选择侵入性治疗之前必须进行准确诊断。仔细记录症状,重点关注它们如何干扰患者的生活质量,以及使用适当选择的检查,是做出正确诊断的主要方法。症状轻微或中度且未出现并发症的男性是药物治疗的理想人选。对于其余有持续症状或并发症(如感染、出血、慢性尿潴留或肾功能损害)的患者,则需要考虑进一步检查和更具侵入性的治疗方式。我们综述了该疾病的病理生理学以及当前针对这一常见问题的方法和管理。