Welge-Lüssen A, Gudziol H
Hals-Nasen-Ohren-Universitätsklinik, Kantonsspital Basel, Basel.
Ther Umsch. 2004 May;61(5):302-7. doi: 10.1024/0040-5930.61.5.302.
Taste disorders can be subdivided in ageusia, which is the inability to detect any qualitative gustatory sensation and hypogeusia, which is a decreased sensitivity to all tastants. Dysgeusia or pargeusia is a distortion or perversion in the perception of a tastant in contrast to phantosmia, which is a perception of taste that occurs in the absence of a tastant. The site of lesion can usually be determined by history and clinical examination. History taking should always include the assessment of current and former medication. Conditions that interfere with access of a tastant to the taste bud are differentiated from conditions that either injure the receptor cell or damage the gustatory afferent nerves and the central pathways. Psychophysical taste evaluation includes identification of quality using sprays or taste strips and testing of intensity perception measuring threshold using the 3-drop technique. Moreover, measurement of taste in localized areas can be performed either with conventional chemicals or using an electrogustometer. Gustatory evoked potentials are not yet routinely elicited. Therapy has to be planned according to the cause of the disorder.
味觉障碍可细分为味觉缺失(即无法察觉任何性质的味觉感觉)和味觉减退(即对所有味觉刺激物的敏感性降低)。味觉异常或幻味是指对味觉刺激物的感知出现扭曲或错乱,与之相对的是幻嗅,即不存在味觉刺激物时却出现味觉感知。病变部位通常可通过病史和临床检查来确定。病史采集应始终包括对当前和既往用药情况的评估。干扰味觉刺激物接触味蕾的情况与损伤受体细胞或损害味觉传入神经及中枢通路的情况有所不同。心理物理学味觉评估包括使用喷雾或味觉试纸进行味觉性质鉴定,以及使用三点滴技术测量强度感知阈值来测试强度感知。此外,局部区域的味觉测量可使用传统化学物质或电味觉计进行。味觉诱发电位尚未常规引出。治疗必须根据障碍的病因来规划。