Puncuh Franco, Lampugnani Elisabetta, Kokki Hannu
Department of Anaesthesiology and Intensive Care, G.Gaslini Children Hospital, L.go G.Gaslini, Genova, Italy.
Paediatr Anaesth. 2004 Jul;14(7):564-7. doi: 10.1111/j.1460-9592.2004.01240.x.
Spinal anaesthesia has been used in children for over 100 years and in the last two decades its popularity for newborns and infants has increased, but there are still unanswered questions with the technique.
We evaluated the characteristics of spinal block including ease of performance, efficacy, adverse effects and complications in 1132 children, aged 6 months to 14 years, undergoing surgery in the lower part of the body. Local ethical committee approved the protocol of this prospective study, and parents gave written informed consent and older children their assent. All patients were sedated with midazolam, thiopental or propofol intravenously during spontaneous ventilation. No inhalation anaesthetics were used. Spinal block was performed with 0.5% hyperbaric bupivacaine at a dose of 0.2 mg x kg(-1).
Efficacy, safety and ease of performance of the spinal block were shown to be satisfactory in most children. Only 27 of the 1132 children needed any supplementation. The incidence and severity of complications was low. Only nine of 942 children, < 10 years of age and eight of 190 children, 10 years or older, developed hypotension. The incidences of postdural puncture headache, in five of the 1132 children, and backache, in nine of the 1132, were low. No other neurological complications were reported.
Spinal anaesthesia with hyperbaric bupivacaine is a feasible anaesthetic method in children for surgery in the lower part of the body.
脊髓麻醉应用于儿童已有100多年历史,在过去二十年中,其在新生儿和婴儿中的应用越来越普遍,但该技术仍存在一些未解决的问题。
我们评估了1132例年龄在6个月至14岁之间接受下半身手术的儿童的脊髓阻滞特征,包括操作难易程度、效果、不良反应和并发症。当地伦理委员会批准了这项前瞻性研究方案,父母给予书面知情同意,年龄较大的儿童表示同意。所有患者在自主通气期间静脉注射咪达唑仑、硫喷妥钠或丙泊酚进行镇静。未使用吸入麻醉剂。采用0.5%重比重布比卡因,剂量为0.2mg·kg⁻¹进行脊髓阻滞。
大多数儿童的脊髓阻滞效果、安全性和操作难易程度令人满意。1132例儿童中只有27例需要补充麻醉。并发症的发生率和严重程度较低。942例年龄小于10岁的儿童中只有9例,190例10岁及以上的儿童中有8例出现低血压。1132例儿童中有5例发生硬膜穿刺后头痛,9例发生背痛,发生率较低。未报告其他神经并发症。
重比重布比卡因脊髓麻醉是儿童下半身手术可行的麻醉方法。