Zeleznik Anthony J
Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Reprod Biol Endocrinol. 2004 Jun 16;2:31. doi: 10.1186/1477-7827-2-31.
During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. In assisted reproductive technology procedures, it is desirable to override the natural process of follicle selection to produce many oocytes that are capable of being fertilized and undergoing normal embryo development. The goal of this chapter is to summarize the current views regarding the natural process of follicle selection in primates and to discuss how this process may be amplified to produce a greater number of oocytes.
在灵长类动物月经周期的卵泡期,通常有一个卵泡成熟至排卵前期并释放其卵母细胞用于受精以及可能的妊娠着床。在辅助生殖技术操作中,期望超越卵泡选择的自然过程,以产生许多能够受精并经历正常胚胎发育的卵母细胞。本章的目的是总结关于灵长类动物卵泡选择自然过程的当前观点,并讨论如何放大这一过程以产生更多数量的卵母细胞。