[血友病性关节病]

Gandini Giorgio, Franchini Massimo

Recenti Prog Med. 2004 May;95(5):259-64.

Hemarthrosis is the most frequent clinical manifestation of severe hemophilia. Recurrent hemarthroses in a joint lead to the development of anatomical changes which result, through an intermediate stage called chronic synovitis, in degenerative arthritis, an extremely disabling disease. In this review, we briefly report the main physio-pathologic, clinic and therapeutic characteristics of the hemophilic arthropathy.

关节积血是严重血友病最常见的临床表现。关节反复出现积血会导致解剖结构改变，经过一个称为慢性滑膜炎的中间阶段，进而发展为退行性关节炎，这是一种极其致残的疾病。在本综述中，我们简要报告血友病性关节病的主要生理病理、临床和治疗特点。