Kerr Roger
Department of Radiology, Orthopaedic Hospital, Los Angeles, CA 90007, USA.
Semin Musculoskelet Radiol. 2003 Jun;7(2):127-36. doi: 10.1055/s-2003-41346.
In patients with hemophilia, hemarthrosis often occurs in one or several joints and may progress to a destructive, disabling arthropathy. Treatment includes continuous or on-demand clotting factor replacement and radionuclide or open synovectomy. The radiographic findings of hemophilic arthropathy depend on the stage of disease, the age of the patient at onset, and the joint involved. These findings include joint effusion, soft tissue swelling, epiphyseal overgrowth, subchondral cysts, osseous erosion, and secondary degenerative changes. Magnetic resonance imaging (MRI) is the most accurate imaging modality for assessing hemophilic arthropathy and may have a significant impact on patient management. MRI is anticipated to be useful in documenting early joint changes when treatment may be most effective. Hemophilic pseudotumor is a chronic, encapsulated, hemorrhagic fluid collection that usually destroys bone and may become quite large. Both computed tomography and MRI are useful in determining the extent of this lesion.
在血友病患者中，关节积血常发生于一个或多个关节，且可能进展为破坏性、致残性关节病。治疗方法包括持续或按需进行凝血因子替代以及放射性核素或开放性滑膜切除术。血友病性关节病的影像学表现取决于疾病阶段、发病时患者的年龄以及受累关节。这些表现包括关节积液、软组织肿胀、骨骺过度生长、软骨下囊肿、骨质侵蚀以及继发性退行性改变。磁共振成像（MRI）是评估血友病性关节病最准确的成像方式，可能对患者的管理产生重大影响。预计MRI在记录早期关节变化时很有用，此时治疗可能最有效。血友病性假肿瘤是一种慢性、有包膜的出血性积液，通常会破坏骨质，且可能变得相当大。计算机断层扫描和MRI在确定该病变的范围方面都很有用。
