Dehbashi S, Honarvar M, Fardi F H
Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Gynaecol Obstet. 2004 Jul;86(1):12-5. doi: 10.1016/j.ijgo.2003.11.001.
To compare the effect of manual removal and spontaneous delivery of placenta on postcesarean bleeding and endometritis.
In this prospective study 400 pregnant women undergoing elective cesarean delivery were randomly assigned to two groups: spontaneous placental delivery (200 women) and manual placental delivery (200). No antibiotic prophylaxis was administered in either group. The significance of blood loss due to cesarean delivery was defined by a drop in hemoglobin concentration of more than 1 g/dl 24 h after delivery in comparison with preoperative hemoglobin concentration. Endometritis was diagnosed in patients who developed clinical signs of fever and suprapubic tenderness 48 h after delivery. We analyzed the data using a t-test.
The overall endometritis rate was 27%, in 40 women in the spontaneous placental delivery group (20%) and 68 women in the manual placental removal group (34%). There was a statistically significant difference between the two groups (P=0.001). Significant blood loss was experienced by 52 women (26%) in the spontaneous placental delivery group vs. 100 women (50%) in the manual placental delivery group. There was a statistically significant difference in blood loss between the two groups (P=0.000; RR=1.92).
Endometritis and blood loss in cesarean delivery is increased by manual removal of the placenta compared with the spontaneous method of placental removal.
比较胎盘人工剥离与自然娩出对剖宫产术后出血及子宫内膜炎的影响。
在这项前瞻性研究中,400例行择期剖宫产的孕妇被随机分为两组:胎盘自然娩出组(200例)和胎盘人工剥离组(200例)。两组均未预防性使用抗生素。剖宫产术后出血的严重程度通过产后24小时血红蛋白浓度较术前下降超过1 g/dl来定义。产后48小时出现发热及耻骨上压痛等临床症状的患者被诊断为子宫内膜炎。我们使用t检验分析数据。
总体子宫内膜炎发生率为27%,胎盘自然娩出组40例(20%),胎盘人工剥离组68例(34%)。两组之间存在统计学显著差异(P = 0.001)。胎盘自然娩出组52例(26%)出现显著失血,而胎盘人工剥离组为100例(50%)。两组间失血量存在统计学显著差异(P = 0.000;RR = 1.92)。
与胎盘自然娩出方法相比,胎盘人工剥离会增加剖宫产术后子宫内膜炎的发生率及失血量。