Claerhout Andrea J, Johnson Michael, Radtke Jennifer D, Zaglaniczny Karen L
St John's Medical Center, Detroit, Mich., USA.
AANA J. 2004 Jun;72(3):225-31.
An increasing number of surgical patients preoperatively are taking anticoagulant medications. These patients are at an increased risk for development of epidural hematoma with spinal or epidural anesthesia. It is the responsibility of the anesthesia provider to understand and anticipate this risk and to alter the anesthetic plan accordingly. The purpose of this AANA Journal course is to update anesthesia providers regarding the common anticoagulants used for surgical patients, the risks associated with epidural and spinal anesthesia in conjunction with anticoagulation, and recommendations for the use of epidural and spinal anesthesia in anticoagulated patients. Antiplatelet drugs, oral anticoagulants, heparin, low-molecular-weight heparin, other new anticoagulants, and herbal medications are reviewed. When spinal or epidural anesthesia is considered for a patient who has been taking anticoagulant medications, the risk of epidural hematoma vs the benefits of regional anesthesia must be weighed carefully. Appropriate management of the patient extends well into the postoperative period and should include anesthesia providers, attending physicians, and nurses.
越来越多的外科手术患者在术前服用抗凝药物。这些患者在接受脊髓或硬膜外麻醉时发生硬膜外血肿的风险增加。麻醉医生有责任了解并预见这种风险,并相应地调整麻醉方案。本《AANA杂志》课程的目的是让麻醉医生了解用于外科手术患者的常见抗凝剂、硬膜外和脊髓麻醉与抗凝联合使用的风险,以及对抗凝患者使用硬膜外和脊髓麻醉的建议。本文回顾抗血小板药物、口服抗凝剂、肝素、低分子量肝素、其他新型抗凝剂和草药。当考虑为服用抗凝药物的患者实施脊髓或硬膜外麻醉时,必须仔细权衡硬膜外血肿的风险与区域麻醉的益处。对患者的妥善管理应贯穿术后很长一段时间,且应包括麻醉医生、主治医生和护士。