Sadaniantz Ara, Katz Alan, Wu Wen-Chih
Division of Cardiology, The Miriam Hospital, Providence, Rhode Island, USA.
Echocardiography. 2004 Jul;21(5):477-84. doi: 10.1111/j.0742-2822.2004.03084.x.
To date, the usage of exercise echocardiography in patients with pulmonary or congenital heart disease has been limited despite its potential for broader applications in different clinical scenarios. Exercise echocardiography can be utilized to determine the extent of pulmonary vascular damage in patients with chronic obstructive pulmonary disease by demonstrating the presence of exertional pulmonary hypertension in subjects with normal pulmonary artery pressures (PAPs) at rest. It is also useful in patients with connective tissue disease to screen for lung involvement by identifying exertional pulmonary hypertension, and in patients with established pulmonary hypertension to choose and monitor the effects of therapeutic interventions on the PAPs. Moreover, the measurement of aortic flow velocity and acceleration by exercise echocardiography may be helpful in the study of dyspnea in patients at risk for both pulmonary disease and congestive heart failure. In patients with congenital heart disease, the measurement of PAP and ventricular function both at rest and during exercise by echocardiography is the cornerstone in the investigation of the etiology of exercise intolerance in these individuals. Lastly, exercise echocardiography can also screen for residual narrowing in patients after repair of the coarctation of the aorta by detecting a significant diastolic gradient in the descending aorta during exercise provocation.
迄今为止,运动超声心动图在肺或先天性心脏病患者中的应用一直有限,尽管它在不同临床场景中有更广泛应用的潜力。运动超声心动图可用于通过在静息肺动脉压(PAP)正常的受试者中显示运动性肺动脉高压的存在,来确定慢性阻塞性肺疾病患者的肺血管损伤程度。它在结缔组织病患者中也很有用,可通过识别运动性肺动脉高压来筛查肺部受累情况,在已确诊肺动脉高压的患者中,可用于选择和监测治疗干预对PAP的影响。此外,通过运动超声心动图测量主动脉流速和加速度可能有助于研究同时患有肺部疾病和充血性心力衰竭风险患者的呼吸困难情况。在先天性心脏病患者中,通过超声心动图测量静息和运动时的PAP及心室功能是调查这些个体运动不耐受病因的基石。最后,运动超声心动图还可通过在运动激发试验期间检测降主动脉中显著的舒张期梯度,来筛查主动脉缩窄修复术后患者的残余狭窄情况。