Chilukuri Suneel, Peterson S Ray, Goldberg Leonard H
Department of Dermatology, Baylor College of Medicine, Houston, Texas 77030, USA.
Dermatol Surg. 2004 Jul;30(7):1046-9. doi: 10.1111/j.1524-4725.2004.30315.x.
Granular cell tumors, also known as granular cell myoblastomas, are uncommon neoplasms of unknown etiology. Most granular cell tumors are benign and present as solitary, painless dermal nodules of the head and neck. Few of these tumors are reported on the lower extremities and only eight cases of granular cell tumor of the foot have been reported. Of these eight, only two clinically benign granular cell tumors occurred on the heel.
The objective was to describe the first reported case of malignant granular cell tumor of the heel.
All reported cases of granular cell tumor of the foot are reviewed and clinical details of a malignant granular cell tumor of the heel are provided.
The malignant granular cell tumor of the heel was extirpated with two stages of Mohs microscopic surgery. No recurrence was noted at 22 months.
Malignant granular cell tumor of the heel is among the rarest of malignancies. In this case, the tumor appears to have been successfully treated with Mohs micrographic surgery.
颗粒细胞瘤,也称为颗粒细胞成肌细胞瘤,是病因不明的罕见肿瘤。大多数颗粒细胞瘤是良性的,表现为头颈部孤立、无痛的皮肤结节。这些肿瘤很少见于下肢,仅报告过8例足部颗粒细胞瘤。其中,仅2例临床良性颗粒细胞瘤发生于足跟。
目的是描述首例报告的足跟恶性颗粒细胞瘤病例。
回顾所有报告的足部颗粒细胞瘤病例,并提供足跟恶性颗粒细胞瘤的临床细节。
足跟恶性颗粒细胞瘤通过两阶段莫氏显微外科手术切除。22个月时未发现复发。
足跟恶性颗粒细胞瘤是最罕见的恶性肿瘤之一。在本病例中,该肿瘤似乎已通过莫氏显微手术成功治疗。