Balzan M, Cacciottolo J M
Department of Medicine, St Luke's Hospital, Malta.
Br J Psychiatry. 1992 Aug;161:257-8. doi: 10.1192/bjp.161.2.257.
A 50-year-old man presented with hyperosmolar non-ketotic diabetic coma associated with the neuroleptic malignant syndrome (NMS) after intramuscular treatment with haloperidol. It is suggested that NMS may occur as a complication of uncontrolled diabetes mellitus with dehydration. Conversely, NMS might precipitate diabetic coma in patients with previously well controlled blood glucose.
一名50岁男性在接受肌肉注射氟哌啶醇治疗后,出现了与抗精神病药物恶性综合征(NMS)相关的高渗性非酮症糖尿病昏迷。提示NMS可能作为未控制的糖尿病伴脱水的并发症出现。相反,NMS可能会使既往血糖控制良好的患者发生糖尿病昏迷。