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[Experimental study progress of tracheal allografts undergoing revascularization and reepithelialization].

作者信息

Yang Jicheng, Hu Jianguo

机构信息

Department of Thoracic Surgery, Central Hospital of Changsha, Changsha, Hunan, 410004, P. R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2004 May;18(3):236-8.

PMID:15211845
Abstract

OBJECTIVE

To study the research advance in tracheal allografts undergoing revascularization and reepithelialization.

METHODS

The recent literature concerned was reviewed. The tracheal allografts are embedded in the omentum, which they were revascularized and reepithelialized by planting in self-epithelia, then the allografts with their omental pedicles were transplanted orthotopically to the cervical or the thoracic portion of the trachea.

RESULTS

Compared with the one-stage tracheal allograft approach using the greater omentum, the two-stage approach could increase the successful rate of revascularization and reepithelialization, and made the allografts accord with their physiology.

CONCLUSION

If the approach is successful, it can reduce graft-rejection, prevent graft-collapse and increase graft-viability after tracheal allograft.

摘要

相似文献

1
[Experimental study progress of tracheal allografts undergoing revascularization and reepithelialization].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2004 May;18(3):236-8.
2
Role of airway epithelial injury in murine orthotopic tracheal allograft rejection.气道上皮损伤在小鼠原位气管同种异体移植排斥反应中的作用。
Ann Thorac Surg. 2006 Oct;82(4):1226-33. doi: 10.1016/j.athoracsur.2006.03.122.
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Reepithelialization of orthotopic tracheal allografts prevents rejection after withdrawal of immunosuppression.原位气管同种异体移植物的再上皮化可防止免疫抑制撤除后的排斥反应。
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[Experimental tracheal reconstruction by allotransplantation].[同种异体移植实验性气管重建]
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Reepithelialized orthotopic tracheal allografts expand memory cytotoxic T lymphocytes but show no evidence of chronic rejection.重新上皮化的原位气管同种异体移植可扩增记忆性细胞毒性T淋巴细胞,但未显示出慢性排斥反应的迹象。
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Heterotopic tracheal transplantation with omentum wrapping in the abdominal position preserves functional and structural integrity of a human tracheal allograft.腹部位置带网膜包裹的异位气管移植可保持人气管同种异体移植物的功能和结构完整性。
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