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转化型难治性贫血伴原始细胞增多(RAEB-T)中的8号和11号染色体三体。

Trisomy 8 and 11 in refractory anemia with excess blasts in transformation (RAEB-T).

作者信息

Ramirez W R, Rosenthal C J, Gogineni S K, Verma R S

机构信息

Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn 11201.

出版信息

Cancer Genet Cytogenet. 1992 Aug;62(1):98-9. doi: 10.1016/0165-4608(92)90048-d.

Abstract

There are no specific chromosomal abnormalities associated with refractory anemia with excess blasts in transformation [RAEB-T]. An 80-year-old white male with RAEB-T was found to have trisomies of chromosomes 8 and 11, i.e., 48,XY,+8,+11. To our knowledge, this chromosomal abnormality in RAEB-T has not been previously reported.

摘要

转化型伴过多原始细胞的难治性贫血(RAEB-T)没有特定的染色体异常。一名80岁患有RAEB-T的白人男性被发现有8号和11号染色体三体,即48,XY,+8,+11。据我们所知,这种RAEB-T中的染色体异常以前尚未有过报道。

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