Yonge Laura, Gracheva Svetlana, Wilkins Shelley J, Livingstone Callum, Davis James
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, UK.
J Am Chem Soc. 2004 Jun 30;126(25):7732-3. doi: 10.1021/ja048093y.
The potentiometric responses of mono- and macromolecular thiol species derivatized with a naphthoquinone indicator have been assessed at electrode designs based on laminated carbon fiber assemblies. The nature of the response for each type of species was found to depend strongly on the electrode geometry and composition and can be used to discriminate between the different thiol moieties. The efficacy of the electrode systems for the measurement of plasma thiols within normal and diabetic blood samples has been assessed, and a possible mechanism for the differing responses has been proposed.
用萘醌指示剂衍生的单分子和大分子硫醇物种的电位响应已在基于层压碳纤维组件的电极设计上进行了评估。发现每种类型物种的响应性质在很大程度上取决于电极的几何形状和组成，并且可用于区分不同的硫醇部分。已经评估了电极系统在正常和糖尿病血液样本中测量血浆硫醇的功效，并提出了不同响应的可能机制。
