Madridejos-Mora Rosa, Amado-Guirado Ester, Pérez-Rodríguez M Teresa
Dirección de Atención Primaria l'Hospitalet, Institut Català de la Salut, Barcelona, Spain.
Med Care. 2004 Jul;42(7):643-8. doi: 10.1097/01.mlr.0000129495.43422.58.
Although there is a great concern regarding rational use of drugs, the available evidence for the most appropriate strategies to improve prescribing is scarce.
The goal of this study was to evaluate the effectiveness of the combination of feedback of individualized prescribing data and educational recommendations for improving the quality of prescribing in general practice.
A quasiexperimental intervention study was conducted in which prescribing rates of 282 family physicians before and after the intervention were compared. Physicians assigned to the individualized feedback group (n = 195) received individual instruction with specific recommendations for improvement according to their baseline prescribing quality levels, whereas physicians in the minimal intervention group (n = 87) only received standard nonindividualized prescribing data for the practice group as a whole.
A trend toward increasing high pharmacologic intrinsic value in both groups was observed. Overprescription of antibiotics showed a decrease in the individualized feedback group (P = 0.006) and it did not change in the minimal intervention group. A different trend in the values in each group was observed with nonsteroidal antiinflammatory drugs, although it was not statistically significant. Overprescription of antiulcerative agents decreased among physicians in the individualized feedback group (P = 0.003); however, there were not statistically significant differences as compared with the minimal intervention group. Changes in indicators of drug selection were more favorable for the group with individualized feedback, although no statistically significant differences were observed. Pharmaceutical expenditure increased significantly in the minimal intervention group as compared with the individualized feedback group, with an approximate difference of dollars 7.87 per inhabitant and trimester (P = 0.003).
The intervention showed that improving the quality of prescribing was feasible, particularly in overprescribing, and was associated with considerable savings in pharmaceutical costs.
尽管人们非常关注药物的合理使用,但关于改善处方开具的最合适策略的现有证据却很少。
本研究的目的是评估个性化处方数据反馈与教育建议相结合对于提高全科医疗中处方开具质量的有效性。
进行了一项准实验性干预研究,比较了282名家庭医生在干预前后的处方开具率。分配到个性化反馈组(n = 195)的医生根据其基线处方质量水平接受了带有具体改进建议的个人指导,而最小干预组(n = 87)的医生仅收到了整个执业组的标准非个性化处方数据。
两组中高药理学内在价值均有增加的趋势。个性化反馈组中抗生素的过度开具有所减少(P = 0.006),而最小干预组中未发生变化。非甾体抗炎药在每组中的值呈现不同趋势,尽管无统计学意义。个性化反馈组中抗溃疡药的过度开具有所减少(P = 0.003);然而,与最小干预组相比,差异无统计学意义。药物选择指标的变化对个性化反馈组更为有利,尽管未观察到统计学上的显著差异。与个性化反馈组相比,最小干预组的药品支出显著增加,人均每三个月约相差7.87美元(P = 0.003)。
该干预表明,提高处方开具质量是可行的,尤其是在过度开具方面,并且与药品成本的大幅节省相关。