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大鼠呼吸中枢向延髓头端腹外侧区的轴突投射。

Axonal projections from respiratory centres towards the rostral ventrolateral medulla in the rat.

作者信息

Pilowsky P, Wakefield B, Minson J, Llewellyn-Smith I, Chalmers J

机构信息

Department of Medicine, Flinders University of South Australia, Bedford Park.

出版信息

Clin Exp Pharmacol Physiol. 1992 May;19(5):335-8. doi: 10.1111/j.1440-1681.1992.tb00466.x.

DOI:10.1111/j.1440-1681.1992.tb00466.x
PMID:1521365
Abstract
  1. Efferent pathways from brainstem respiratory centres towards bulbospinal tyrosine hydroxylase immunoreactive neurons were identified in the rat using a combination of electrophysiology, retrograde and anterograde tract-tracing, and immunohistochemistry. 2. Varicose axons originating from respiratory centres were found in close apposition to bulbospinal tyrosine hydroxylase immunoreactive neurons in the ventrolateral medulla. 3. These findings support the idea that respiratory rhythms in sympathetic nerves may be due to a synaptic connection between brainstem respiratory neurons and bulbospinal tyrosine hydroxylase immunoreactive neurons of the C1 cell group.
摘要
  1. 运用电生理学、逆行和顺行示踪技术以及免疫组织化学相结合的方法,在大鼠中确定了从脑干呼吸中枢到延髓脊髓酪氨酸羟化酶免疫反应性神经元的传出通路。2. 发现源自呼吸中枢的曲张轴突与延髓腹外侧的延髓脊髓酪氨酸羟化酶免疫反应性神经元紧密相邻。3. 这些发现支持这样一种观点,即交感神经中的呼吸节律可能归因于脑干呼吸神经元与C1细胞群的延髓脊髓酪氨酸羟化酶免疫反应性神经元之间的突触连接。

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