Cengiz A Bülent, Kara Ateş, Kanra Güler, Seçmeer Gülten, Ceyhan Mehmet, Ozen Metehan
Section of Infectious Diseases, Department of Pediatrics, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2004 Apr-Jun;46(2):153-8.
A retrospective review was conducted on 132 patients aged between two and 15 years with cervical lymphadenitis and/or with abscess formation to determine the epidemiologic and clinical presentation of these infections. The most common locations were the upper anterior cervical space (43.2%) and the submandibular space (27.3%). The duration of symptoms ranged from 12 hours to 20 days. Results of the pus cultures were available in 31 patients (23.5%). Of these, 16 cultures (51.6%) were positive. The isolated organisms were Staphylococcus aureus (50%), Staphylococcus epidermidis (31.3%), group A beta-hemolytic streptococcus (12.5%), Streptococcus pneumoniae (6.3%) and Escherichia coli (6.3%). One of the specimens yielded mixed organisms (Staphylococcus epidermidis and Streptococcus pneumoniae). Penicillin resistance was documented in six (37.5%) of the 16 gram-positive bacteria isolated from the pus culture. Both throat and blood cultures were available in all 132 patients. Seven throat cultures (5.3%) were positive for group A beta hemolytic streptococci, whereas five blood cultures (3.8%) were reported to have bacterial growth. Sixty-seven patients (50.8%) were treated with ampicillin-sulbactam, 53 patients (40.1%) with ampicillin-sulbactam and ornidazole and 12 patients (9.1%) with ceftriaxone parenterally. The mean duration of hospital stay related to the infection was 7.30 +/- 3.89 days (range, 2-28 days). The mean period for downsizing of the cervical mass by half was 4.05 +/- 2.05 days, and the recovery period (total antibiotic usage period) was 13.72 +/- 5.33 days. All of the patients had an uneventful recovery without complications. Results of both throat and blood cultures were not predictive for etiologic agents in our study group. Since ultrasonographic evaluation of each patient has limited additional benefits in clinical management, it must be reserved for selected cases to document abscess formation.
对132例年龄在2至15岁之间患有颈淋巴结炎和/或伴有脓肿形成的患者进行了回顾性研究,以确定这些感染的流行病学和临床表现。最常见的部位是颈前上部间隙(43.2%)和下颌下间隙(27.3%)。症状持续时间从12小时至20天不等。31例患者(23.5%)有脓液培养结果。其中,16份培养物(51.6%)呈阳性。分离出的微生物有金黄色葡萄球菌(50%)、表皮葡萄球菌(31.3%)、A组β溶血性链球菌(12.5%)、肺炎链球菌(6.3%)和大肠杆菌(6.3%)。其中一份标本培养出混合菌(表皮葡萄球菌和肺炎链球菌)。从脓液培养物中分离出的16株革兰氏阳性菌中有6株(37.5%)记录有青霉素耐药性。所有132例患者均进行了咽喉和血液培养。7份咽喉培养物(5.3%)A组β溶血性链球菌呈阳性,而5份血液培养物(3.8%)报告有细菌生长。67例患者(50.8%)接受了氨苄西林-舒巴坦治疗,53例患者(40.1%)接受了氨苄西林-舒巴坦和奥硝唑治疗,12例患者(9.1%)接受了头孢曲松静脉注射治疗。与感染相关的平均住院时间为7.30±3.89天(范围为2至28天)。颈部肿块缩小一半的平均时间为4.05±2.05天,恢复期(总抗生素使用期)为13.72±5.33天。所有患者均顺利康复,无并发症。在我们的研究组中,咽喉和血液培养结果均不能预测病原体。由于对每位患者进行超声检查在临床管理中的额外益处有限,因此必须保留用于特定病例以记录脓肿形成情况。