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使用自我报告数据估计社区居住老年人的相对健康状况和虚弱程度。

The estimation of relative fitness and frailty in community-dwelling older adults using self-report data.

作者信息

Mitnitski Arnold B, Song Xiaowei, Rockwood Kenneth

机构信息

Division of Geriatric Medicine, Dalhousie University, Suite 1421, 5955 Veterans' Memorial Lane Rd., Halifax, NS, B3H 2E1, Canada.

出版信息

J Gerontol A Biol Sci Med Sci. 2004 Jun;59(6):M627-32. doi: 10.1093/gerona/59.6.m627.

Abstract

BACKGROUND

While on average health declines with age, it also becomes more variable with age. As a consequence of this marked variability, it becomes more important as people age to have a means of summarizing health status, but how precisely to do so remains controversial. We developed one measure of health status, personal biological age, from a frailty index. The index itself is a count of deficits derived, in the first instance, from a clinical database. In our earlier investigations, personal biological age demonstrated a strong relationship with 6-year survival. Here we extend this approach to self-reported data.

METHODS

This is a secondary analysis of community-dwelling people aged 65 years and older (n = 9008) in the Canadian Study of Health and Aging. The frailty index was calculated from 40 self-reported variables, representing symptoms, attitudes, illnesses, and function. Personal biological age was estimated for each individual as the age corresponding to the mean chronological age for the index value. Individual frailty (and the related construct of fitness) was calculated as the difference between chronological and personal biological age.

RESULTS

The frailty index showed, on average, an exponential increase with age at an average rate of 3% per year. Although women, on average, demonstrate more frailty than men of the same chronological age, their survival chances are greater. The frailty index strongly correlated (Pearson r =.992 for women and.955 for men) with survival.

CONCLUSIONS

A frailty index, based on self-report data, can be used as a tool for capturing heterogeneity in the health status of older adults.

摘要

背景

虽然健康状况平均会随着年龄增长而下降,但年龄增长也会使其变得更具变异性。由于这种显著的变异性,随着人们年龄的增长,拥有一种总结健康状况的方法变得更加重要,但如何准确做到这一点仍存在争议。我们从衰弱指数中开发了一种健康状况衡量指标,即个人生物学年龄。该指数本身是对最初从临床数据库得出的缺陷进行计数。在我们早期的研究中,个人生物学年龄与6年生存率显示出很强的相关性。在此,我们将这种方法扩展到自我报告数据。

方法

这是对加拿大健康与老龄化研究中65岁及以上社区居住人群(n = 9008)的二次分析。衰弱指数由40个自我报告变量计算得出,这些变量代表症状、态度、疾病和功能。为每个个体估计个人生物学年龄,即与该指数值对应的平均实际年龄相同的年龄。个体衰弱(以及相关的健康状况概念)通过实际年龄与个人生物学年龄的差值来计算。

结果

衰弱指数平均每年以3%的速度随年龄呈指数增长。虽然平均而言,女性比同实际年龄的男性表现出更多的衰弱,但她们的生存机会更大。衰弱指数与生存率密切相关(女性的皮尔逊r值为0.992,男性为0.955)。

结论

基于自我报告数据的衰弱指数可作为一种工具,用于捕捉老年人健康状况的异质性。

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