van Gelder Rogier E, Venema Henk W, Florie Jasper, Nio C Yung, Serlie Iwo W O, Schutter Michiel P, van Rijn Jeroen C, Vos Frans M, Glas Afina S, Bossuyt Patrick M M, Bartelsman Joep F W, Laméris Johan S, Stoker Jaap
Department of Radiology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Radiology. 2004 Aug;232(2):611-20. doi: 10.1148/radiol.2322031069. Epub 2004 Jun 23.
In a feasibility study, the authors compared polyp detection and interobserver variability at computed tomographic (CT) colonography in 15 patients with doses ranging from medium to very low (12.00-0.05 mSv). At levels down to 2% of the medium dose, the mean detection of polyps 5 mm or larger remained at least 74%, while the number of false-positive results decreased and the interobserver agreement remained constant. Initial observations indicate that it is feasible to reduce the radiation dose required for CT colonography. Further studies are needed, however, to investigate the clinical value of very low-dose CT colonography.
在一项可行性研究中，作者比较了15例患者在计算机断层扫描（CT）结肠造影中，使用从中等剂量到极低剂量（12.00 - 0.05毫希沃特）的情况下息肉检测情况及观察者间的差异。在低至中等剂量2%的水平下，直径5毫米或更大息肉的平均检测率至少保持在74%，而假阳性结果数量减少，观察者间的一致性保持不变。初步观察表明，降低CT结肠造影所需的辐射剂量是可行的。然而，还需要进一步研究来调查极低剂量CT结肠造影的临床价值。
