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垂体瘤、QT间期延长与室性心律失常

PITUITARY TUMOR, QT PROLONGATION AND VENTRICULAR ARRHYTHMIA.

作者信息

Petrovich Lawrence J., Adyanthaya Ajit V., Dillman Robert, Alexander James K.

机构信息

Ben Taub General Hospital and Baylor College of Medicine, Houston, Texas.

出版信息

Cardiovasc Dis. 1978 Mar;5(1):32-36.

PMID:15216077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC287702/
Abstract

Various types of nervous system diseases have been associated with QT prolongation and ventricular arrhythmias. This report describes a young woman with a pituitary tumor, who had QT prolongation and recurrent syncope secondary to ventricular fibrillation. Effective therapy with digoxin and propranolol are described, and pathophysiology of the syndrome is discussed.

摘要

多种类型的神经系统疾病已被发现与QT间期延长和室性心律失常有关。本报告描述了一名患有垂体瘤的年轻女性,她因室颤继发QT间期延长和反复晕厥。文中介绍了地高辛和普萘洛尔的有效治疗方法,并讨论了该综合征的病理生理学。

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本文引用的文献

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Electrocardiographic changes simulating myocardial ischemia and infarction associated with spontaneous intracranial hemorrhage.模拟心肌缺血和梗死的心电图改变与自发性颅内出血相关。
Circulation. 1960 Jul;22:25-38. doi: 10.1161/01.cir.22.1.25.
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Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval and sudden death.先天性聋哑、伴有Q-T间期延长的功能性心脏病及猝死。
Am Heart J. 1957 Jul;54(1):59-68. doi: 10.1016/0002-8703(57)90079-0.
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The surdo-cardiac syndrome: three new cases of congenital deafness with syncopal attacks and Q-T prolongation in the electrocardiogram.聋哑-心脏综合征:3例先天性耳聋合并晕厥发作及心电图Q-T间期延长的新病例
Am Heart J. 1966 Nov;72(5):582-93. doi: 10.1016/0002-8703(66)90340-1.
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Heritable Q-T prolongation without deafness.遗传性Q-T间期延长但无耳聋。
Circulation. 1970 Jan;41(1):39-48. doi: 10.1161/01.cir.41.1.39.
5
Experimental production of magnesium deficiency in man.人体镁缺乏的实验性产生。
Ann N Y Acad Sci. 1969 Aug 15;162(2):847-55. doi: 10.1111/j.1749-6632.1969.tb13014.x.
6
QT-interval prolongation, paroxysmal ventricular arrhythmias, and convulsive syncope.QT间期延长、阵发性室性心律失常和惊厥性晕厥。
Ann Intern Med. 1971 Dec;75(6):919-24. doi: 10.7326/0003-4819-75-6-919.
7
Unilateral cervicothoracic sympathetic ganglionectomy for the treatment of long QT interval syndrome.单侧颈胸交感神经节切除术治疗长QT间期综合征
N Engl J Med. 1971 Oct 14;285(16):903-4. doi: 10.1056/NEJM197110142851607.
8
Functional distribution of right and left stellate innervation to the ventricles. Production of neurogenic electrocardiographic changes by unilateral alteration of sympathetic tone.左右星状神经对心室的功能性分布。通过单侧交感神经张力改变产生神经源性心电图变化。
Circ Res. 1966 Apr;18(4):416-28. doi: 10.1161/01.res.18.4.416.
9
Cardiac abnormalities in subarachnoid hemorrhage: a resumé.蛛网膜下腔出血时的心脏异常:一份综述
Stroke. 1974 May-Jun;5(3):384-92. doi: 10.1161/01.str.5.3.384.
10
Q-T interval syndromes.
Prog Cardiovasc Dis. 1974 May-Jun;16(6):523-30. doi: 10.1016/0033-0620(74)90016-4.