源自[Cr(CO)3(η6-5,8-萘醌)]的内消旋二醇配合物的去对称化：新型二胺酰化催化剂的应用
Desymmetrization of a meso-diol complex derived from [Cr(CO)3(eta6-5,8-naphthoquinone)]: use of new diamine acylation catalysts.
作者信息
Kündig E Peter, Lomberget Thierry, Bragg Ryan, Poulard Cyril, Bernardinelli Gérald
机构信息
Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland.
出版信息
Chem Commun (Camb). 2004 Jul 7(13):1548-9. doi: 10.1039/b404006f. Epub 2004 May 21.
DOI:10.1039/b404006f
PMID:15216374
Abstract
Cr(CO)3(naphthoquinone), prepared in a three-step sequence starting from 1,4-dihydroxynaphthalene, was reduced to the corresponding meso-dihydronaphthalene syn-diol complex and the latter was desymmetrized to give the mono-acyl complex with 99% ee via asymmetric acylation catalyzed by the two new and easily accessed chiral diamines 7 and 8.
摘要
由1,4-二羟基萘经三步反应制备得到的Cr(CO)₃(萘醌)被还原为相应的内消旋二氢萘顺式二醇配合物，后者通过由两种新型且易于获得的手性二胺7和8催化的不对称酰化反应进行去对称化，得到ee值为99%的单酰基配合物。
Zotero 插件