Traxer Olivier, Gattegno Bernard
Service d'Urologie, Hôpital Tenon, Paris, France.
Prog Urol. 2004 Apr;14(2):249-51.
The rationale for intravesical chemotherapy in the treatment of superficial bladder tumours is based on the knowledge of their natural history, particularly the propensity of a majority of tumours to relapses, while only a small proportion of these tumours present a risk of progression. The objective of intravesical chemotherapy is to prevent tumour implantation on the site of resection and to eliminate any residual disease responsible for recurrences; this treatment therefore constitutes "chemoprophylaxis". The objective of this technical note is to recall the practical modalities of early postoperative mitomycin C instillation with particular emphasis on two technical points.
膀胱内化疗用于治疗浅表性膀胱肿瘤的理论依据基于对其自然病史的了解，特别是大多数肿瘤有复发倾向，而只有一小部分这些肿瘤存在进展风险。膀胱内化疗的目的是防止肿瘤种植在切除部位，并消除任何导致复发的残留病灶；因此这种治疗构成“化学预防”。本技术说明的目的是回顾术后早期丝裂霉素C灌注的实际操作方式，特别强调两个技术要点。
