Parra Covarrubias A, Ramós Galván R
Gac Med Mex. 1992 Jan-Feb;128(1):7-13.
The plasma concentrations of FSH and LH were measured in 250 boys with psychosocial deprivation (PSD) aged 9.0-15.9 years and in 357 clinically healthy boys of the same age. The results were correlated with chronological age (CA), weight, height and calculated lean body mass (LBM) and total body fat (TBT). On a group basis, PSD boys had the clinical onset of puberty at 13.9 years, while healthy boys did so at 11.9 years. In both groups, the mean weights at time of initiation of the adolescent growth spurt and time of peak velocity of weight gain were very close to each other and the same phenomenon was true for their heights and the amount of LBM. Based on CA mean plasma FSH concentrations in PSD boys and a steep rise two years later than in healthy boys; however, when analyzed as a function of body weight, height or LBM, no such difference emerged. On the other hand, mean plasma LH concentrations in PSD boys were higher than in healthy boys only up to 12.9 years, 42.9 kg of body weight, a height of 142.0 cms and LBM of 32.0 kg; however, no steep rise in plasma LH was observed in contrast to healthy boys. No correlations was observed between TBF and plasma gonadotropins. Therefore, although on the basis of CA, PSD boys had a delayed onset in plasma gonadotropins changes, this occurred in association with the attainment of similar body weight, height and LBM as in healthy boys.(ABSTRACT TRUNCATED AT 250 WORDS)
对250名年龄在9.0至15.9岁之间遭受心理社会剥夺（PSD）的男孩以及357名同龄临床健康男孩的促卵泡激素（FSH）和促黄体生成素（LH）血浆浓度进行了测量。结果与实际年龄（CA）、体重、身高以及计算得出的瘦体重（LBM）和体脂总量（TBT）相关。从群体来看，PSD男孩青春期临床启动年龄为13.9岁，而健康男孩为11.9岁。在两组中，青春期生长突增开始时的平均体重以及体重增加峰值速度时的平均体重彼此非常接近，身高和LBM量也呈现同样的现象。基于CA，PSD男孩的平均血浆FSH浓度比健康男孩晚两年急剧上升；然而，当按体重、身高或LBM进行分析时，未出现这种差异。另一方面，PSD男孩的平均血浆LH浓度仅在12.9岁、体重42.9千克、身高142.0厘米和LBM为32.0千克之前高于健康男孩；然而，与健康男孩不同，未观察到血浆LH急剧上升。未观察到TBF与血浆促性腺激素之间存在相关性。因此，尽管基于CA，PSD男孩血浆促性腺激素变化的启动延迟，但这与达到与健康男孩相似的体重、身高和LBM有关。（摘要截断于250字）
