Graesslin O, Martin-Morille C, Dedecker F, Gabriel R, Quereux C
Service de gynécologie obstétrique, institut Mère-Enfant Alix-de-Champagne, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims, France.
Gynecol Obstet Fertil. 2004 Jun;32(6):519-24. doi: 10.1016/j.gyobfe.2004.03.018.
The majority of sacrococcygeal teratomas diagnosed before birth can be managed by planned delivery and postnatal surgery. However, large tumors early in gestation may result in placentomegaly, hydrops and fetal death and a preeclampsia-like syndrome in the mother. This is due to high output cardiac failure in the fetus caused by arteriovenous shunting through the tumor. In these cases, in utero treatment may offer improved chances of survival, and emerging technologies should lower fetal and maternal morbidity. Nevertheless, these therapeutics need to be correctly evaluated.
大多数在出生前被诊断出的骶尾部畸胎瘤可以通过计划分娩和出生后手术来处理。然而,妊娠早期的大肿瘤可能导致胎盘肿大、胎儿水肿和胎儿死亡,以及母亲出现类似先兆子痫的综合征。这是由于通过肿瘤的动静脉分流导致胎儿出现高输出量心力衰竭。在这些情况下,宫内治疗可能会提高存活几率,并且新兴技术应能降低胎儿和母亲的发病率。尽管如此,这些治疗方法仍需要得到正确评估。