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肾上腺皮质癌同时分泌醛固酮和皮质醇。

Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma.

作者信息

Kurtulmus Neslihan, Yarman Sema, Azizlerli Halil, Kapran Yersu

机构信息

Division of Endocrinology, Metabolism and Nutrition, Departmant of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey.

出版信息

Horm Res. 2004;62(2):67-70. doi: 10.1159/000079322. Epub 2004 Jun 21.

Abstract

We report a rare case of adrenocortical carcinoma. A 26-year-old woman presented with hypokalemia and hypertension due to hyperaldosteronism. She had no signs of Cushing's syndrome. Endocrinological data showed excess of aldosterone production and nonsupressible cortisol production on 2 mg of dexamethasone. Magnetic resonance imaging showed left adrenal tumor. Transabdominal left adrenalectomy was performed and histopathological diagnosis was adrenocortical carcinoma. Her blood pressure and hypokalemia returned to normal after adrenalectomy. There is no recurrence after 36 months. We want to emphasis the importance of adrenal tests before the operation even if there are no signs of excess cortisol production.

摘要

我们报告一例罕见的肾上腺皮质癌病例。一名26岁女性因醛固酮增多症出现低钾血症和高血压。她没有库欣综合征的体征。内分泌学检查数据显示醛固酮分泌过多,且给予2毫克地塞米松后皮质醇分泌不可抑制。磁共振成像显示左侧肾上腺肿瘤。行经腹左侧肾上腺切除术,组织病理学诊断为肾上腺皮质癌。肾上腺切除术后她的血压和低钾血症恢复正常。36个月后无复发。我们想强调即使没有皮质醇分泌过多的体征,术前进行肾上腺检查的重要性。

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