Mavrikakis I, Mavrikakis E, Syam P P, Bell J, Casey J Hickman, Casswell A G, Brittain G P, Liu C
Sussex Eye Hospital, Brighton and Sussex University Hospitals, Brighton, UK.
Eye (Lond). 2005 Feb;19(2):205-9. doi: 10.1038/sj.eye.6701448.
To evaluate the safety and efficacy of surgical implantation of prosthetic iris devices in patients with iris deficiency.
Nine patients with traumatic iris defects, congenital aniridia or iris coloboma, and surgical or optical iridectomies were included in a noncomparative case series. Cataract surgery with intraocular lens and prosthetic iris implantation was performed in 10 eyes. The visual acuity, subjective degree of glare disability, postoperative anatomic results, and intraoperative and postoperative complications were evaluated.
The mean follow-up was 17.75 months (range 4-48 months). Best-corrected visual acuity improved in nine of 10 eyes (90%) and remained unchanged in one eye. Glare subjectively improved in four of five eyes (80%) of patients complaining of glare preoperatively. All eyes achieved the desired anatomic result. Intraoperative complications included one anterior capsular tear. Postoperative complications included a short period of mild postoperative anterior uveitis in four eyes. Secondary glaucoma was absent.
In patients with iris deficiency, implantation of prosthetic iris device, and intraocular lens implant following cataract surgery appears to be safe and effective in reducing glare disability and improving visual outcomes.
评估人工虹膜装置手术植入治疗虹膜缺损患者的安全性和有效性。
一项非对照病例系列纳入了9例患有外伤性虹膜缺损、先天性无虹膜或虹膜缺损以及接受过手术或光学虹膜切除术的患者。对10只眼进行了白内障摘除联合人工晶状体植入及人工虹膜植入手术。评估了视力、主观眩光障碍程度、术后解剖结果以及术中及术后并发症。
平均随访时间为17.75个月(范围4 - 48个月)。10只眼中9只眼(90%)的最佳矫正视力提高,1只眼保持不变。术前抱怨有眩光的患者中,5只眼中4只眼(80%)的眩光主观上有所改善。所有术眼均达到预期解剖效果。术中并发症包括1例前囊膜撕裂。术后并发症包括4只眼短期轻度术后前葡萄膜炎。无继发性青光眼发生。
对于虹膜缺损患者,白内障手术后植入人工虹膜装置及人工晶状体似乎在减少眩光障碍和改善视力预后方面是安全有效的。