Muñoz Díaz A B, Aguilar P
Servicio de Nefrología, Hospital General Universitario La Fe, Valencia.
Nefrologia. 2004;24 Suppl 3:76-80.
A 32-year-old male patient was admitted at our department presenting microhematuria and full nephrotic syndrome in April 1995. A percutaneous kidney biopsy showed a stage I-lI membranous nephropathy and an eight-week course with oral prednisone was initiated without response. Then, oral cyclosporine A (3.5 mg/kg/day) was given and after 5 weeks of treatment, remission of the nephrotic syndrome was observed but creatinine raised to 1.6 mg/dl, normalizing after reducing the dose of cyclosporine A. We discuss the settings, prognostic and therapeutic alternatives for idiopathic membranous nephropathy.
一名32岁男性患者于1995年4月入住我科，表现为镜下血尿和完全性肾病综合征。经皮肾活检显示为I-II期膜性肾病，开始口服泼尼松治疗8周但无反应。随后给予口服环孢素A（3.5mg/kg/天），治疗5周后肾病综合征缓解，但肌酐升至1.6mg/dl，减少环孢素A剂量后肌酐恢复正常。我们讨论了特发性膜性肾病的发病情况、预后及治疗选择。
