利用光学相干断层扫描对角膜钙化病变进行成像与定量分析。
Imaging and quantification of calcified corneal lesions with optical coherence tomography.
作者信息
Wirbelauer Christopher, Pham Duy Thoai
机构信息
Klinik für Augenheilkunde, Vivantes Klinikum Neukölln, Rudower Str. 48, D-12351 Berlin, Germany.
出版信息
Cornea. 2004 Jul;23(5):439-42. doi: 10.1097/01.ico.0000114121.05360.19.
PURPOSE
The purpose of this study was to image and quantify calcified corneal lesions with optical coherence tomography (OCT) and to evaluate this diagnostic method to assess this corneal disease.
METHODS
In a clinical study 15 eyes of 14 patients with calcified corneal lesions in the anterior portions of the cornea were assessed with slit-lamp biomicroscopy and slit-lamp-adapted OCT. The qualitative and quantitative optical changes were compared with the clinical findings.
RESULTS
In corneal OCT all calcified lesions revealed marked hyperreflective changes that correlated well with macroscopic findings. Dense calcified lesions resulted in partial or complete shadowing of the posterior corneal structures. The thickness values for the hyperreflective calcified lesions ranged from 27 to 344 microm.
CONCLUSION
Noncontact slit-lamp-adapted OCT may be of value in assessing calcified corneal lesions. Corneal OCT could also be used to precisely measure the depth of these corneal processes and evaluate treatment modalities.
目的
本研究旨在利用光学相干断层扫描（OCT）对角膜钙化病变进行成像和定量分析，并评估这种诊断方法用于评估此类角膜疾病的效果。
方法
在一项临床研究中，对14例角膜前部有钙化病变患者的15只眼睛进行了裂隙灯生物显微镜检查和裂隙灯适配OCT评估。将定性和定量光学变化与临床检查结果进行比较。
结果
在角膜OCT检查中，所有钙化病变均显示出明显的高反射变化，与宏观检查结果密切相关。致密的钙化病变导致角膜后部结构部分或完全遮挡。高反射钙化病变的厚度值范围为27至344微米。
结论
非接触式裂隙灯适配OCT在评估角膜钙化病变方面可能具有价值。角膜OCT还可用于精确测量这些角膜病变的深度并评估治疗方式。
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