Swennen Gwen, Berten Johannes-Ludwig, Kramer Franz-Josef, Malevez Chantal, De Mey Albert, Schwestka-Polly Rainer, Hausamen Jarg-Erich
Department of Oral and Maxillofacial Surgery, Hannover Medical School, Hannover, Germany.
Cleft Palate Craniofac J. 2004 Jul;41(4):403-9. doi: 10.1597/02-165.1.
The purpose of this study was to evaluate and compare mandibular morphology and spatial position in children with complete unilateral cleft lip and palate (UCLP) treated at two different cleft centers (Hannover and Brussels) following different surgical treatment protocols.
A total of 62 Caucasian children (40 boys, 22 girls) with nonsyndromic complete unilateral cleft lip and palate (UCLP) were evaluated by means of conventional cephalometric analysis at approximately the age of 10 years. Data of both cleft groups were compared with a control, noncleft group (n = 40) matched according to age and sex.
The Hannover children with cleft (n = 36) underwent lip repair at a mean age of 5.83 +/- 1.16 months. The hard and soft palates were closed at a mean age of 29.08 +/- 4.68 and 32.25 +/- 4.29 months, respectively. The Brussels children with cleft (n = 26) were treated according to the Malek surgical protocol with soft palate repair at a mean age of 3.04 +/- 0.20 months and simultaneous lip and hard palate repair at a mean age of 6.15 +/- 0.68 months.
Statistical analysis (analysis of variance with post hoc Tukey's test) showed a significant (p =.001) smaller mandibular ramus length (Co-Go) in the Brussels cleft group, compared with the control group. The Hannover-Brussels comparison data revealed that the S-N-B angle was significantly (p =.047) less in the Brussels cleft group.
The influence of surgical procedures in patients with UCLP might not be restricted to the maxilla but could influence mandibular spatial position to the cranial base. Because of these positional changes of the mandible, both cleft groups showed facial balance.
本研究旨在评估和比较在两个不同腭裂治疗中心(汉诺威和布鲁塞尔)按照不同手术治疗方案接受治疗的单侧完全性唇腭裂(UCLP)患儿的下颌骨形态和空间位置。
共有62名非综合征性单侧完全性唇腭裂(UCLP)的白种儿童(40名男孩,22名女孩)在大约10岁时通过传统头影测量分析进行评估。将两个腭裂组的数据与根据年龄和性别匹配的非腭裂对照组(n = 40)进行比较。
汉诺威的腭裂患儿(n = 36)平均在5.83 +/- 1.16个月时进行唇裂修复。硬腭和软腭分别在平均29.08 +/- 4.68个月和32.25 +/- 4.29个月时闭合。布鲁塞尔的腭裂患儿(n = 26)按照马利克手术方案进行治疗,软腭修复平均年龄为3.04 +/- 0.20个月,唇裂和硬腭同时修复平均年龄为6.15 +/- 0.68个月。
统计分析(方差分析及事后Tukey检验)显示,与对照组相比,布鲁塞尔腭裂组的下颌升支长度(Co-Go)明显更小(p =.001)。汉诺威-布鲁塞尔的比较数据显示,布鲁塞尔腭裂组的S-N-B角明显更小(p =.047)。
UCLP患者手术操作的影响可能不仅限于上颌骨,还可能影响下颌骨相对于颅底的空间位置。由于下颌骨的这些位置变化,两个腭裂组均表现出面部平衡。