De Mey A, Swennen G, Malevez C, George M, Mansbach A L
Department of plastic surgery, Free University Brussels, Belgium.
B-ENT. 2006;2 Suppl 4:44-50.
The purpose of this retrospective of prospectively acquired data was to evaluate and to compare global evolution in children with complete unilateral cleft lip and palate treated at the Brussels cleft centre following two different surgical treatment protocols.
A series of forty-four patients operated for non-syndromic complete unilateral cleft lip and palate were included in this study at the age of approximately ten years. Twenty-six children (17 males, 9 females) were treated according to the Malek surgical treatment protocol: the soft palate was closed at a mean age of 3 months, followed by simultaneous repair of the lip and hard palate at a mean age of 6 months. Eighteen children (15 males, 3 females) underwent one-stage "all-in-one" closure of the lip, hard and soft palate at a mean age of 3 months. Craniofacial morphology was evaluated by means of digital lateral cephalometric analysis. Cephalometric data were compared to a control, non-cleft group (n = 40) matched according to age. Data concerning otological status and speech were collected in the same series of children.
Statistical analysis showed that the inclination of the maxillary (MxPVSN) plane to the anterior cranial base was significantly increased (p <0.001) in both cleft groups compared to the non-cleft group and significantly increased (p = 0.002) in the Malek cleft group compared to the "all-in-one" cleft group. Otological status was not improved by an early complete closure but by close follow-up and the repeated placement of ventilating tubes. Speech was found to be satisfactory in the majority of children of both groups at six years after speech therapy. Only 15% needed further surgery with pharyngeal flaps.
There were no significant differences in anteroposterior midfacial morphology between the Malek and "all-in-one" protocols at ten years of age. One-stage "all-in-one" closure resulted in less downward inclination of the maxillary plane to the anterior cranial base compared to the Malek protocol at ten years of age. Early complete closure of the cleft resulted in no significant change in otological status or the occurrence of nasality. However, early complete closure of the cleft allowed for earlier intelligibility of speech compared to the staged later closure.
本次对前瞻性收集数据的回顾性研究旨在评估和比较在布鲁塞尔腭裂中心接受两种不同手术治疗方案的单侧完全性唇腭裂患儿的整体发育情况。
本研究纳入了一系列44例接受非综合征性单侧完全性唇腭裂手术的患者,年龄约为10岁。26名儿童(17名男性,9名女性)按照马利克手术治疗方案进行治疗:软腭在平均3个月龄时闭合,随后在平均6个月龄时同时修复唇和硬腭。18名儿童(15名男性,3名女性)在平均3个月龄时接受唇、硬腭和软腭的一期“一体化”闭合手术。通过数字化侧位头影测量分析评估颅面形态。将头影测量数据与根据年龄匹配的非腭裂对照组(n = 40)进行比较。在同一组儿童中收集有关耳科状况和语音的数据。
统计分析表明,与非腭裂组相比,两个腭裂组的上颌(MxPVSN)平面相对于前颅底的倾斜度均显著增加(p <0.001),与“一体化”腭裂组相比,马利克腭裂组的倾斜度显著增加(p = 0.002)。早期完全闭合并不能改善耳科状况,但密切随访和反复放置通气管可以改善。在接受语音治疗6年后,两组大多数儿童的语音情况令人满意。只有15%的儿童需要进一步进行咽瓣手术。
在10岁时,马利克方案和“一体化”方案在前后面部中部形态上没有显著差异。与马利克方案相比,10岁时一期“一体化”闭合导致上颌平面相对于前颅底的向下倾斜度较小。腭裂的早期完全闭合在耳科状况或鼻音发生率方面没有显著变化。然而,与分期较晚闭合相比,腭裂的早期完全闭合使语音清晰度提高得更早。