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多发性嗜铬细胞瘤(作者译)

[Multiple phaeochomocytomas (author's transl)].

作者信息

Schindler G, Hippéli R, Longin F

出版信息

Rofo. 1978 Oct;129(4):454-60. doi: 10.1055/s-0029-1231139.

Abstract

Multiple phaeochromocytomas represent a polytopic form of chromaffin tumours. The tumours may arise simultaneously or sequentially in chromaffin tissue, particularly in the retroperitoneal space. Malignancy can only be assumed if there are metastases to organs which do not contain chromaffin tissue. Their origin may be regarded as a dysontogenetic event. The clinical picture is dominated by the excretion of catecholamines. Laboratory tests are therefore used to determine the suspicion of the presence of a chromaffin tumour. A patient with an eight-year history is described, who had had four operations and in whom, by radiology or surgery, seven phaeochromocytomas had been found. The value of various radiological methods is discussed. The most informative method is arteriography; in view of the possibility of multiple tumours, aortography should be carried out in the first instance.

摘要

多发性嗜铬细胞瘤是嗜铬细胞瘤的一种多部位发生形式。肿瘤可在嗜铬组织中同时或相继出现,尤其是在腹膜后间隙。只有当出现向不含嗜铬组织的器官转移时,才能认定为恶性。其起源可被视为一种发育异常事件。临床表现以儿茶酚胺分泌为主。因此,实验室检查用于确定是否怀疑存在嗜铬细胞瘤。本文描述了一名有八年病史的患者,该患者接受了四次手术,通过放射学或手术发现了七个嗜铬细胞瘤。讨论了各种放射学方法的价值。最具诊断价值的方法是动脉造影;鉴于存在多个肿瘤的可能性,应首先进行主动脉造影。

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