Bachthaler Maike, Lenhart Markus, Paetzel Christian, Feuerbach Stefan, Link Johann, Manke Christoph
Department of Diagnostic Radiology, University Hospital of Regensburg, Regensburg, Germany.
Catheter Cardiovasc Interv. 2004 Jul;62(3):380-4. doi: 10.1002/ccd.20113.
The purpose of this study was to evaluate coil corrosion and the long-term outcome after peripheral vascular embolization therapy performed with tungsten coils. We studied 14 patients who received tungsten coils on an average of 26 months prior to follow-up. The protocol included plain radiography and contrast-enhanced magnetic resonance angiography to investigate corrosion of tungsten coils and recanalization of the embolized vessels. Whole blood, hair, and urine tungsten levels were assayed when available. Corrosion of tungsten coils was detected in 9 of 14 patients by plain radiography. No evidence of recanalization of the embolized vessel and no adverse clinical effects of tungsten resorption were detected. Blood levels of tungsten were elevated in 6 of 14 patients and urine levels of tungsten were elevated in all 12 patients tested. Tungsten coil corrosion and elevated tungsten levels in blood, hair, and urine were found in most patients, although no adverse clinical effects of tungsten resorption were detected. Since the overall effect of high tungsten blood levels remains unclear, its use as an implant should be avoided.
本研究的目的是评估使用钨丝弹簧圈进行外周血管栓塞治疗后的弹簧圈腐蚀情况及长期预后。我们研究了14例患者，他们在随访前平均26个月接受了钨丝弹簧圈治疗。研究方案包括X线平片和对比增强磁共振血管造影，以调查钨丝弹簧圈的腐蚀情况和栓塞血管的再通情况。如有可用样本，还对全血、头发和尿液中的钨含量进行了检测。通过X线平片在14例患者中的9例检测到钨丝弹簧圈腐蚀。未检测到栓塞血管再通的证据，也未检测到钨吸收的不良临床影响。14例患者中有6例血液中的钨含量升高，所有12例接受检测的患者尿液中的钨含量均升高。大多数患者发现有钨丝弹簧圈腐蚀以及血液、头发和尿液中的钨含量升高，尽管未检测到钨吸收的不良临床影响。由于高钨血水平的总体影响尚不清楚，应避免将其用作植入物。
