Solowski Nancy L, Yao Francisca Brunelle, Agarwal Anurag, Nagorsky Matthew
Drexel University College of Medicine, Philadelphia, PA, USA.
Ann Otol Rhinol Laryngol. 2004 Jun;113(6):462-4. doi: 10.1177/000348940411300609.
Ecthyma gangrenosum is a cutaneous lesion frequently associated with Pseudomonas aeruginosa bacteremia, although it may develop in the absence of bacteremia and may originate from other bacterial and fungal organisms. Ecthyma gangrenosum most often occurs in patients with neutropenia and other immunocompromised hosts. It typically occurs on the extremities and gluteal and perineal regions. We report a rare case of ecthyma gangrenosum presenting as an aggressive necrotic skin lesion on the nasal ala of a patient with myelofibrosis. Tissue and blood cultures were positive for P aeruginosa. This clinical entity should be considered when otolaryngologists are asked to evaluate necrotic cutaneous lesions of the head and neck.
坏疽性脓皮病是一种常与铜绿假单胞菌败血症相关的皮肤病变，尽管它可能在无败血症的情况下发生，并且可能源自其他细菌和真菌。坏疽性脓皮病最常发生在中性粒细胞减少症患者和其他免疫功能低下的宿主中。它通常发生在四肢、臀部和会阴区域。我们报告了一例罕见的坏疽性脓皮病病例，表现为骨髓纤维化患者鼻翼上的侵袭性坏死性皮肤病变。组织和血液培养显示铜绿假单胞菌阳性。当耳鼻喉科医生被要求评估头颈部坏死性皮肤病变时，应考虑这种临床情况。
