Park Keehyun, Moon Sung-Kyun, Cho Min Jung, Won Ye Yeon, Baek Myon Ghyun
Department of Otolaryngology, Ajou University School of Medicine, Suwon, South Korea.
Acta Otolaryngol. 2004 May;124(4):403-7. doi: 10.1080/00016480410016496.
To reconstruct the 3D structures of normal ossicles and ossicles destroyed by different cholesteatomas, and to compare the volume fractions of the two types of ossicles.
Thirteen pathological ossicles from four kinds of middle ear cholesteatoma obtained during surgery were used. Normal ossicles harvested from cadaveric temporal bone specimens were used as controls. The structures of the ossicles were analyzed using micro-CT by filming 2D cross-sectional images perpendicular to the long axis, from which 3D images were reconstructed. The volume fraction was measured using a CT-Analyzer and Ant.
The volume fraction, indicating the relative strength of normal ossicles, was lower in the portion close to the articular surface. As the four types of cholesteatoma were found to express their patterns of destruction at various sites in the ossicles, they revealed a different volume fraction in each ossicle.
Our preliminary data on ossicular structure obtained using micro-CT will be helpful for elucidating the normal and pathological structure of ossicles and for the further development of artificial prostheses.
重建正常听小骨及被不同胆脂瘤破坏的听小骨的三维结构，并比较两种听小骨的体积分数。
使用手术中获取的来自四种中耳胆脂瘤的13个病理听小骨。取自尸体颞骨标本的正常听小骨用作对照。通过拍摄垂直于长轴的二维横截面图像，利用微型计算机断层扫描（micro-CT）分析听小骨的结构，从中重建三维图像。使用CT分析仪和Ant测量体积分数。
表明正常听小骨相对强度的体积分数在靠近关节面的部分较低。由于发现四种类型的胆脂瘤在听小骨的不同部位表现出其破坏模式，它们在每个听小骨中显示出不同的体积分数。
我们使用微型计算机断层扫描获得的关于听小骨结构的初步数据将有助于阐明听小骨的正常和病理结构以及人工假体的进一步开发。
