Clayton Julie
J Biol. 2004;3(3):9. doi: 10.1186/jbiol9. Epub 2004 Jun 28.
Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.
小鼠胚胎肺部发育过程中Wnt信号通路的组成性激活会导致一些细胞发育出类似肠道的表型。这些发现让人联想到经典的胚胎学实验，并且可能对癌前化生具有治疗意义。
