新型喹诺酮类药物是否适合用于社区获得性耐甲氧西林金黄色葡萄球菌感染的治疗？
Are the new quinolones appropriate treatment for community-acquired methicillin-resistant Staphylococcus aureus?
作者信息
Shopsin Bo, Zhao Xilin, Kreiswirth Barry N, Tillotson Glenn S, Drlica Karl
机构信息
Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
出版信息
Int J Antimicrob Agents. 2004 Jul;24(1):32-4. doi: 10.1016/j.ijantimicag.2004.03.009.
Abstract
The use of quinolones in the treatment of non-serious community-acquired methicillin-resistant Staphylococcus aureus is discussed. The new C8-modified quinolones may be suitable for such treatment but controlled trials should be carried out to ensure that the pharmacokinetics are such that there is little risk of resistance developing.
摘要
讨论了喹诺酮类药物在治疗非重症社区获得性耐甲氧西林金黄色葡萄球菌感染中的应用。新型C8修饰喹诺酮类药物可能适用于此类治疗，但应进行对照试验，以确保其药代动力学特性不会导致产生耐药性的风险。
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