利奈唑胺成功治疗耐甲氧西林金黄色葡萄球菌心内膜炎。
Successful treatment of methicillin-resistant Staphylococcus aureus endocarditis with linezolid.
作者信息
Bassetti Matteo, Di Biagio Antonio, Del Bono Valerio, Cenderello Giovanni, Bassetti Dante
机构信息
Department of Infectious Diseases, San Martino Hospital, University of Genoa, School of Medicine, Genoa, Italy.
出版信息
Int J Antimicrob Agents. 2004 Jul;24(1):83-4. doi: 10.1016/j.ijantimicag.2003.12.018.
We report the successful treatment with linezolid of a methicillin-resistant Staphylococcus aureus (MRSA) endocarditis in a patient with a severe allergic reaction to glycopeptides. Linezolid is a drug with well-recognised activity against S. aureus and proved to be efficacious even in the unusual site of heart valves. This drug could be a good therapeutic choice when glycopeptides treatment is not feasible.
我们报告了1例对糖肽类药物严重过敏的耐甲氧西林金黄色葡萄球菌（MRSA）心内膜炎患者使用利奈唑胺成功治疗的病例。利奈唑胺是一种对金黄色葡萄球菌具有公认活性的药物，事实证明即使在心脏瓣膜这一特殊部位也有效。当糖肽类药物治疗不可行时，这种药物可能是一个很好的治疗选择。
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