Wilkins C E, Betancourt B, Mathur V S, Massumi A, De Castro C M, Garcia E, Hall R J
Clayton Foundation for Research Cardiovascular Laboratories and the Department of Cardiology, St. Luke's Episcopal Hospital and the Texas Heart Institute, Houston, Texas, USA.
Tex Heart Inst J. 1988;15(3):166-73.
We reviewed the records of 10,661 patients who had undergone coronary angiography at the Clayton Foundation Cardiovascular Laboratories between 1 June 1974 and 15 March 1986, and identified major coronary artery anomalies in 83 adults. In addition, we included in our review 9 adults and 2 adolescents who had been referred for evaluation of anomalies documented elsewhere. Here we present the clinical and angiographic data for all 94 patients (76 men and 18 women). Most patients were men who presented with chest pain. The most common anomaly, found in 38 patients, was origin of left circumflex coronary artery from right coronary artery or right aortic sinus. In contrast to other studies, which have not shown increased incidence of coronary atherosclerosis in the anomalous circumflex artery, 71% of our patients with this anomaly had significant coronary atherosclerosis in the proximal portion of the anomalous vessel. The posterior course of the anomalous circumflex coronary artery may predispose this vessel to atherosclerosis in patients with coronary disease. The overall incidence of atherosclerotic disease in coronary arteries was 68% (64 of 94 patients) in the present study.
我们回顾了1974年6月1日至1986年3月15日期间在克莱顿基金会心血管实验室接受冠状动脉造影的10661例患者的记录,在83例成年人中发现了主要冠状动脉异常。此外,我们的回顾纳入了9例成年人和2例青少年,他们因其他地方记录的异常情况而被转诊进行评估。在此,我们展示了所有94例患者(76例男性和18例女性)的临床和血管造影数据。大多数患者为出现胸痛的男性。在38例患者中发现的最常见异常是左旋支冠状动脉起源于右冠状动脉或右主动脉窦。与其他未显示异常左旋支动脉中冠状动脉粥样硬化发病率增加的研究不同,我们患有这种异常的患者中有71%在异常血管近端有明显的冠状动脉粥样硬化。异常左旋支冠状动脉的走行可能使患有冠心病的患者该血管易患动脉粥样硬化。在本研究中,冠状动脉中动脉粥样硬化疾病的总体发病率为68%(94例患者中的64例)。