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人工流产方法。

Methods for induced abortion.

作者信息

Stubblefield Phillip G, Carr-Ellis Sacheen, Borgatta Lynn

机构信息

Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts 02118, USA.

出版信息

Obstet Gynecol. 2004 Jul;104(1):174-85. doi: 10.1097/01.AOG.0000130842.21897.53.

Abstract

We describe present methods for induced abortion used in the United States. The most common procedure is first-trimester vacuum curettage. Analgesia is usually provided with a paracervical block and is not completely effective. Pretreatment with nonsteroidal analgesics and conscious sedation augment analgesia but only to a modest extent. Cervical dilation is accomplished with conventional tapered dilators, hygroscopic dilators, or misoprostol. Manual vacuum curettage is as safe and effective as the electric uterine aspirator for procedures through 10 weeks of gestation. Common complications and their management are presented. Early abortion with mifepristone/misoprostol combinations is replacing some surgical abortions. Two mifepristone/misoprostol regimens are used. The rare serious complications of medical abortion are described. Twelve percent of abortions are performed in the second trimester, the majority of these by dilation and evacuation (D&E) after laminaria dilation of the cervix. Uterine evacuation is accomplished with heavy ovum forceps augmented by 14-16 mm vacuum cannula systems. Cervical injection of dilute vasopressin reduces blood loss. Operative ultrasonography is reported to reduce perforation risk of D&E. Dilation and evacuation procedures have evolved to include intact D&E and combination methods for more advanced gestations. Vaginal misoprostol is as effective as dinoprostone for second-trimester labor-induction abortion and appears to be replacing older methods. Mifepristone/misoprostol combinations appear more effective than misoprostol alone. Uterine rupture has been reported in women with uterine scars with misoprostol abortion in the second trimester. Fetal intracardiac injection to reduce multiple pregnancies or selectively abort an anomalous twin is accepted therapy. Outcomes for the remaining pregnancy have improved with experience.

摘要

我们描述了美国目前使用的人工流产方法。最常见的手术是孕早期负压吸宫术。通常采用宫颈旁阻滞进行镇痛,但效果并不完全理想。术前使用非甾体类镇痛药和清醒镇静可增强镇痛效果,但程度有限。宫颈扩张可通过传统的锥形扩张器、吸湿扩张器或米索前列醇来完成。对于妊娠10周以内的手术,手动负压吸宫术与电动子宫吸引器一样安全有效。文中介绍了常见并发症及其处理方法。米非司酮/米索前列醇联合用药的早期流产正在取代一些手术流产。目前使用两种米非司酮/米索前列醇给药方案。文中描述了药物流产罕见的严重并发症。12%的流产发生在孕中期,其中大多数是在宫颈用海藻棒扩张后进行扩张刮宫术(D&E)。使用重型卵圆钳并辅以14 - 16毫米的真空套管系统来完成子宫排空。宫颈注射稀释的血管加压素可减少出血。据报道,手术超声检查可降低扩张刮宫术的穿孔风险。扩张刮宫术已发展到包括完整的扩张刮宫术以及针对更晚期妊娠的联合方法。阴道米索前列醇在孕中期引产流产方面与地诺前列酮效果相同,似乎正在取代旧的方法。米非司酮/米索前列醇联合用药似乎比单独使用米索前列醇更有效。有报道称,孕中期使用米索前列醇流产时,子宫瘢痕女性会发生子宫破裂。胎儿心内注射以减少多胎妊娠或选择性终止异常双胎是公认的治疗方法。随着经验的积累,剩余妊娠的结局有所改善。

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