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急性非静脉曲张性上消化道出血的急诊内镜检查与择期内镜检查:一项有效性研究。

Urgent vs. elective endoscopy for acute non-variceal upper-GI bleeding: an effectiveness study.

作者信息

Bjorkman David J, Zaman Atif, Fennerty M Brian, Lieberman David, Disario James A, Guest-Warnick Ginger

机构信息

Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132-2101, USA.

出版信息

Gastrointest Endosc. 2004 Jul;60(1):1-8. doi: 10.1016/s0016-5107(04)01287-8.

Abstract

BACKGROUND

Urgent endoscopy in patients with acute upper-GI bleeding identifies many patients who may be safely treated without hospitalization. The aim of this multicenter trial was to determine whether urgent endoscopy effectively decreases health care resource utilization in a real-life setting where primary care providers determine the course of care.

METHODS

Ninety-three outpatients with acute upper-GI bleeding were randomized to either urgent endoscopy (before hospitalization) or elective endoscopy after admission. The results of urgent endoscopy and a recommendation regarding patient disposition were provided to the attending physician. Medical outcomes and resource utilization were measured.

RESULTS

The timing of endoscopy did not affect resource utilization or patient outcomes. Length of stay was similar (urgent endoscopy, OR 3.98 days: 95% CI[2.84, 5.11] vs. elective endoscopy, OR 3.26 days: 95% CI[2.32, 4.21], p=0.45). The mean number of days in an intensive care unit was the same (1.2 days). The urgent endoscopy group had more high-risk endoscopic lesions (15 vs. 9; p=0.031). Outpatient care was recommended for 19 patients (40%). Only 4 patients were discharged.

CONCLUSIONS

Urgent endoscopy did not reduce hospitalization or resource utilization because the results of early endoscopy did not impact the decision by attending physicians regarding admission. For early (triage) endoscopy to impact resource utilization, the results of endoscopy must change subsequent patient care.

摘要

背景

急性上消化道出血患者的紧急内镜检查可识别出许多无需住院即可安全治疗的患者。这项多中心试验的目的是确定在初级保健提供者决定治疗过程的现实环境中,紧急内镜检查是否能有效降低医疗资源的使用。

方法

93例急性上消化道出血门诊患者被随机分为紧急内镜检查组(住院前)或入院后择期内镜检查组。将紧急内镜检查结果及关于患者处置的建议提供给主治医生。对医疗结果和资源使用情况进行了测量。

结果

内镜检查的时机不影响资源使用或患者预后。住院时间相似(紧急内镜检查组,平均住院时间3.98天:95%可信区间[2.84, 5.11];择期内镜检查组,平均住院时间3.26天:95%可信区间[2.32, 4.21],p = 0.45)。重症监护病房的平均住院天数相同(1.2天)。紧急内镜检查组有更多的高危内镜病变(15例对9例;p = 0.031)。建议对19例患者(40%)进行门诊治疗。仅4例患者出院。

结论

紧急内镜检查并未减少住院率或资源使用,因为早期内镜检查结果并未影响主治医生关于入院的决定。要使早期(分诊)内镜检查影响资源使用,内镜检查结果必须改变后续的患者治疗。

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