Bonifaz Alexandro, Archer-Dubon Carla, Saúl Amado
Department of Dermatology, Hospital General de México, and Dermatology Service, Instituto Nacional de la Nutrición SS, México City, Mexico.
Int J Dermatol. 2004 Jul;43(7):506-10. doi: 10.1111/j.1365-4632.2004.02171.x.
Tinea imbricata (TI) or Tokelau is a superficial mycosis caused by Trichophyton concentricum, an anthropophilic dermatophyte. It is endemic in some islands of the South Pacific (Polynesia), South-East Asia, Central and South America, and Mexico, and is most often seen in individuals living in primitive and isolated conditions. The skin lesions are characteristically concentric and lamellar (imbricata: in Latin, tiled) plaques of scale. Predisposing conditions include humidity, inheritance, and immunologic factors. The diagnosis is usually made on clinical grounds, supported by skin scrapings and culture. Tokelau is a chronic and highly relapsing disease and, although no first-line treatment exists, best results are obtained with oral griseofulvin and terbinafine and a topical combination of keratolytic ointments, such as Whitfield's. TI is a disease model that allows the correlation of a series of environmental, genetic, immunologic, and therapeutic conditions.
叠瓦癣(TI)或托克劳癣是由亲人性皮肤癣菌同心性毛癣菌引起的一种浅表真菌病。它在南太平洋(波利尼西亚)、东南亚、中美洲、南美洲和墨西哥的一些岛屿上流行,最常见于生活在原始和孤立环境中的个体。皮肤损害的特征是呈同心性和层状(叠瓦状:在拉丁语中为瓦片状)鳞屑斑块。诱发因素包括湿度、遗传和免疫因素。诊断通常基于临床症状,并通过皮肤刮屑和培养来辅助。托克劳癣是一种慢性且极易复发的疾病,尽管没有一线治疗方法,但口服灰黄霉素和特比萘芬以及外用角质溶解软膏(如惠特菲尔德软膏)联合使用可取得最佳效果。TI是一种疾病模型,可用于关联一系列环境、遗传、免疫和治疗条件。