Suppr超能文献

开胸术后镇痛:硬膜外给予芬太尼/布比卡因与肋间神经阻滞加静脉注射吗啡的比较

Analgesia after thoracotomy: epidural fentanyl/bupivacaine compared with intercostal nerve block plus intravenous morphine.

作者信息

Concha Mario, Dagnino Jorge, Cariaga Mario, Aguilera Jorge, Aparicio Rodrigo, Guerrero Mario

机构信息

Department of Anesthesiology, Division of Surgery, Pontificia Universidad Católica de Chile, Santiago, Chile.

出版信息

J Cardiothorac Vasc Anesth. 2004 Jun;18(3):322-6. doi: 10.1053/j.jvca.2004.03.013.

Abstract

OBJECTIVES

Intercostal nerve blockade plus intravenous (IV) patient-controlled analgesia (PCA) could be an easier and safer alternative to epidural analgesia for postthoracotomy pain, but information about the efficacy of this technique is scarce. The objective of this randomized study was to compare the quality of analgesia and lung function in 2 groups of patients undergoing pulmonary surgery through a posterolateral thoracotomy.

METHODS

Two groups were studied: G1 (n = 16) patients received a 5-segment intercostal block plus IV PCA morphine, and G2 (n = 15) patients received a bupivacaine and fentanyl PCA infusion through a thoracic epidural catheter. Resting and dynamic visual analog pain scale (VAS) measurements, forced vital capacity, and forced expiratory volume in 1 second were measured basally, on arrival in the recovery room, then hourly up to 4 hours and then 12, 24 and 48 hours later. Results were analyzed with a 2-way analysis of variance, chi-square, or Fisher exact test. A p value < or =0.05 was considered significant.

RESULTS

Resting and dynamic VAS scores were slightly lower in G2 patients, although only resting scores were significant. After the first hour, mean scores were below 4 in both groups. No significant difference was observed between groups in relation to respiratory parameters or side effects.

CONCLUSION

The fact that the difference in pain scores is probably not clinically significant shows that an intercostal block with bupivacaine plus IV morphine PCA is a good alternative for postthoracotomy pain management.

摘要

目的

对于开胸术后疼痛,肋间神经阻滞联合静脉自控镇痛(PCA)可能是一种比硬膜外镇痛更简便、更安全的替代方法,但关于该技术疗效的信息较少。这项随机研究的目的是比较两组接受后外侧开胸肺手术患者的镇痛质量和肺功能。

方法

研究分为两组:G1组(n = 16)患者接受5节段肋间阻滞联合静脉PCA吗啡,G2组(n = 15)患者通过胸段硬膜外导管接受布比卡因和芬太尼PCA输注。在基础状态、进入恢复室时、之后每小时直至4小时,然后在12、24和48小时后测量静息和动态视觉模拟疼痛量表(VAS)评分、用力肺活量和第1秒用力呼气量。结果采用双向方差分析、卡方检验或Fisher精确检验进行分析。p值≤0.05被认为具有统计学意义。

结果

G2组患者的静息和动态VAS评分略低,尽管只有静息评分具有统计学意义。1小时后,两组的平均评分均低于4分。两组在呼吸参数或副作用方面未观察到显著差异。

结论

疼痛评分差异可能无临床意义这一事实表明,布比卡因肋间阻滞联合静脉吗啡PCA是开胸术后疼痛管理的一种良好替代方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验