Sliwa Leopold
Zakład Biologii Rozwoju Człowieka Collegium Medicum Untwersytetu Jagiellońskiego ul. Kopernika 7, 31-034 Kraków.
Folia Med Cracov. 2003;44(1-2):153-8.
The presented paper is the survey of the most important literature concerning one of the basic biological properties of spermatozoa which is their chemotaxis during the process of fertilization. During the recent years a significant progress in the knowledge of this matter has been observed, especially in relation to human and mammal spermatozoa. A natural chemotactic factor is, in the case of mammals, the vesicle fluid. It is not known, however, which of its components is of the crucial importance. Numerous hormones, cytokines and other growth factors as well as other components of the vesicle fluid have been described as chemoattractants. It can be concluded from the research carried out so far that the chemotactic activity of the vesicle fluid results from its complex composition, and not from the existence of one chemical substance which could be crucial for the process.
本文是对有关精子基本生物学特性之一——受精过程中的趋化性——的最重要文献的综述。近年来,在这一领域的知识方面取得了显著进展,尤其是关于人类和哺乳动物精子的研究。对于哺乳动物而言,一种天然的趋化因子是卵泡液。然而,尚不清楚其哪些成分至关重要。许多激素、细胞因子和其他生长因子以及卵泡液的其他成分都被描述为化学引诱剂。从迄今为止所进行的研究可以得出结论,卵泡液的趋化活性源于其复杂的成分,而非存在一种对该过程至关重要的化学物质。