Hernández Alvarado S R, Guzmán-Grenfell A M, Hicks Gómez J J
Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, México, D.F. México.
Ginecol Obstet Mex. 1995 Aug;63:323-7.
The communication to distance is controlled chemically by the egg and the spermatozoa as part of the fertilization process, it has been studied intensily in invertebrate animals with outside fertilization. However studies with mammals offers a field of great interest. The chemoattractant from mammals spermatozoa include peptides or protein with a molecular weight of 1-20 KDa, hormones like progesterone, oxitocin, adrenalin and receptors on the spermatozoa head which are associated with the Guanylyl cyclase enzyme and G proteins, as well as other as like odorant receptor, rhodoopsin kinases and arresting. Chemotaxis allow us to understand the fertilization in human and also develop program for assisted reproduction. It is very important in the contraception.
卵子和精子在受精过程中通过化学方式控制远距离通讯,这在体外受精的无脊椎动物中已得到深入研究。然而,对哺乳动物的研究提供了一个极具吸引力的领域。哺乳动物精子的化学引诱剂包括分子量为1至20千道尔顿的肽或蛋白质、诸如孕酮、催产素、肾上腺素等激素以及精子头部与鸟苷酸环化酶和G蛋白相关的受体,还有其他诸如气味受体、视紫红质激酶和抑制蛋白。趋化作用有助于我们理解人类的受精过程,也有助于开发辅助生殖程序。它在避孕方面也非常重要。