Lerche R-C, Richard G
Klinik und Poliklinik für Augenheilkunde, Universitäts-Krankenhaus Hamburg-Eppendorf, Hamburg.
Klin Monbl Augenheilkd. 2004 Jun;221(6):479-84. doi: 10.1055/s-2004-813286.
The pathogenesis of branch retinal vein occlusion (BRVO) seems to differ from that of central retinal vein occlusion (CRVO). Arteriosclerotic and anatomic aspects suggest that arteriovenous crossing of vessels may play a significant role. New procedures like arteriovenous decompression have been proposed to be a suitable form of treatment.
In a clinical trial, 12 patients with ischemic BRVO underwent surgical decompression. Strict criteria of inclusion were maintained. Arteriovenous sheathotomy (AVS) was performed 0.5 - 6 months after retinal vein occlusion. Follow up-time was 3 months. Visual acuity and incidence of typical complications after RVO were the main aspects of interest in the scientific evaluation.
After surgical AVS, visual acuity increased significantly from logMAR 0.74 (decimal 0.18) to 0.56 (0.32) in EDTRS charts. Surgical or early complications did not occur during the 3-month control period. Improvement of retinal blood flow during angiography was demonstrated in 75 % of the patients. In 50 % of the patients all non-perfusion areas had disappeared.
For patients with retinal vein occlusion, AVS seems to be a safe and feasible procedure according to the pathogenesis of branch occlusion. Our results suggest that AVS has the potential to improve visual acuity while typical complications due to surgery or vein occlusion do not occur during the first three months.
视网膜分支静脉阻塞(BRVO)的发病机制似乎与视网膜中央静脉阻塞(CRVO)不同。动脉硬化和解剖学方面表明,动静脉交叉处可能起重要作用。已提出诸如动静脉减压等新手术方法作为一种合适的治疗形式。
在一项临床试验中,12例缺血性BRVO患者接受了手术减压。维持严格的纳入标准。在视网膜静脉阻塞后0.5 - 6个月进行动静脉鞘膜切开术(AVS)。随访时间为3个月。视力以及视网膜静脉阻塞(RVO)后典型并发症的发生率是科学评估中主要关注的方面。
在进行手术AVS后,在EDTRS视力表中,视力从logMAR 0.74(小数视力0.18)显著提高至0.56(0.32)。在3个月的对照期内未发生手术或早期并发症。75%的患者在血管造影时显示视网膜血流改善。50%的患者所有无灌注区均消失。
对于视网膜静脉阻塞患者,根据分支阻塞的发病机制,AVS似乎是一种安全可行的手术方法。我们的结果表明,AVS有提高视力的潜力,同时在最初三个月内不会出现因手术或静脉阻塞引起的典型并发症。