Willis S, Hölzl F, Fackeldey V, Schumpelick V
Chirurgische Universitätsklinik und Poliklinik der RWTH Aachen.
Zentralbl Chir. 2004 Jun;129(3):211-5. doi: 10.1055/s-2004-822743.
The following study reports on the effect of biofeedback and transanal electric stimulation as a conservative method in the therapy of idiopathic fecal incontinence. 22 consecutive patients in whom the diagnosis "idiopathic incontinence" was established after endoscopy, endoanal ultrasound and measurement of pudendal nerve terminal motor latency underwent combined sphincter training for 3 months. The results were evaluated prospectively by clinical classification using a modified Kelly-Holschneider-score and anal manometry before and after treatment. Combined biofeedback led to a significant increase of the continence score in 18 of 22 patients (7.7 +/- 3.8 vs. 9.3 +/- 3.0, p = 0.004). Both squeeze (77 +/- 28 mmHg vs. 92 +/- 32 mmHg, p = 0.047) and resting pressures (40 +/- 19 vs. 52 +/- 23 mmHg, p = 0.015) increased significantly during the training period. There were no significant differences in squeeze and resting asymmetry indexes, sensory and urge thresholds and maximal tolerable volumes. The prolongation of biofeedback training from 3 to 6 months in 9 patients did not change clinical or manometric results significantly.
The combination of biofeedback training with anal electrostimulation increases anal squeeze and resting pressures, thus leading to an improvement of clinical incontinence symptoms. Therefore it should be the first choice in the therapy of idiopathic fecal incontinence. A training period of 3 months seems to be sufficient.
以下研究报告了生物反馈和经肛门电刺激作为一种保守方法在特发性大便失禁治疗中的效果。22例经内镜检查、肛门内超声检查及阴部神经终末运动潜伏期测量确诊为“特发性失禁”的连续患者接受了为期3个月的联合括约肌训练。通过使用改良的凯利 - 霍尔施奈德评分进行临床分类,并在治疗前后进行肛门测压,对结果进行前瞻性评估。联合生物反馈使22例患者中的18例(7.7±3.8对9.3±3.0,p = 0.004)的控便评分显著提高。在训练期间,收缩压(77±28 mmHg对92±32 mmHg,p = 0.047)和静息压(40±19对52±23 mmHg,p = 0.015)均显著升高。收缩和静息不对称指数、感觉和急迫阈值以及最大耐受量方面无显著差异。9例患者将生物反馈训练从3个月延长至6个月,临床或测压结果无显著变化。
生物反馈训练与肛门电刺激相结合可增加肛门收缩压和静息压,从而改善临床失禁症状。因此,它应成为特发性大便失禁治疗的首选方法。3个月的训练期似乎就足够了。