Department of Surgical Sciences, Section of General Surgical Clinics and Surgical Therapy, Parma University Medical School, Via Gramsci 14, Parma, 43100, Italy.
World J Surg. 2010 Apr;34(4):815-21. doi: 10.1007/s00268-010-0392-9.
The current literature does not provide unequivocal data on prognostic factors in conservative management of fecal incontinence. Moreover, the physiopathologic effects of pelvic floor rehabilitation on anorectal function are not well understood. Our aim is to identify some prognostic parameters and assess their effects on anorectal physiology of biofeedback therapy plus anal electrostimulation for fecal incontinence.
We studied prospectively 45 consecutive adult patients with fecal incontinence treated at our institution with biofeedback plus electrostimulation. The outcome parameter was modification of the Wexner Incontinence Score (WIS) at the end of treatment. In addition, we studied the modifications of anorectal manometry and the rectal sensitivity threshold after treatment.
At univariate analysis, age, the pretreatment WIS, and the pretreatment resting and maximum squeeze pressures were correlated with the clinical outcome. Patients showed a significant reduction in the rectal sensitivity threshold but no significant change in manometric parameters after treatment.
We identify good sphincter function and mild to moderate symptomatology as favorable prognostic factors in biofeedback and anal electrostimulation therapy. Improvement in rectal sensitivity can be implicated in symptomatic improvement. The impossibility of correlating the clinical results with the effects on anorectal physiology suggests a nonspecific effect of conservative treatment.
目前的文献并没有提供关于粪便失禁保守治疗的明确预后因素的数据。此外,盆底康复对肛肠功能的病理生理影响也不明确。我们的目的是确定一些预后参数,并评估它们对生物反馈治疗加肛门电刺激治疗粪便失禁的肛肠生理学的影响。
我们前瞻性地研究了在我院接受生物反馈加电刺激治疗的 45 例连续成年粪便失禁患者。结局参数是治疗结束时 Wexner 失禁评分(WIS)的改变。此外,我们还研究了治疗后肛门直肠测压和直肠感觉阈值的变化。
单因素分析显示,年龄、治疗前 WIS 以及治疗前静息和最大收缩压与临床结局相关。患者的直肠感觉阈值显著降低,但治疗后测压参数无明显变化。
我们认为肛门括约肌功能良好和症状轻至中度是生物反馈和肛门电刺激治疗的有利预后因素。直肠敏感性的改善可能与症状的改善有关。临床结果与肛肠生理学效应之间无法相关提示保守治疗具有非特异性效应。