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17例患者(20处移植)接受冷冻自体骨和同种异体骨移植的超长期影像学和骨扫描结果:30至35年随访。

Very long-term radiographic and bone scan results of frozen autograft and allograft bone grafting in 17 patients (20 grafts) a 30- to 35-year follow-up.

作者信息

Steinberg Ely L, Luger Elhanan, Zwas Tila, Katznelson Alexander

机构信息

Department of Orthopaedic Surgery 'B', Tel Aviv Sourasky Medical Center.

出版信息

Cell Tissue Bank. 2004;5(2):97-104. doi: 10.1023/B:CATB.0000034084.27772.66.

Abstract

In the early 1950s, 48 patients received bone implants from a bone bank in Tel-Hashomer Hospital that stored frozen autograft and allograft bones at temperatures less than -17 degrees C. Seventeen (35%) of these patients (20 implants), 10 men and 7 women, with a mean age of 52.4 (34-69) years were available for follow-up after a mean period of 32.5 (30-35) years. They underwent clinical examination, radiographs and bone scans to evaluate their surgical results. Fracture healing, non-union, graft resorption, osteoporosis and bone sclerosis were used as radiographic criteria for bone incorporation, and normal, increased and decreased uptake served to assess the bone scan. Based on the above criteria, the results were satisfactory in 17 (85%) and poor in 3 (15%). The three failures were after shelf operation for hip dysplasia that used two allografts and one autograft. Allogenous or a combination of allogenous with autogenous frozen bone grafts proved to be a satisfactory and durable method for filling bone defects.

摘要

20世纪50年代初,48名患者接受了来自特拉维夫哈希默医院骨库的骨植入物,该骨库在低于-17摄氏度的温度下储存冷冻自体骨和异体骨。这些患者中有17名(35%)(20个植入物),10名男性和7名女性,平均年龄52.4岁(34 - 69岁),在平均32.5年(30 - 35年)的随访期后可供评估。他们接受了临床检查、X光片和骨扫描以评估手术效果。骨折愈合、骨不连、移植物吸收、骨质疏松和骨质硬化被用作骨融合的影像学标准,而正常、摄取增加和摄取减少则用于评估骨扫描。基于上述标准,17例(85%)结果令人满意,3例(15%)结果不佳。这三例失败病例均发生在髋关节发育不良的翻修手术之后,手术中使用了两块异体骨和一块自体骨。异体骨或异体骨与自体冷冻骨联合移植被证明是一种令人满意且持久的填充骨缺损的方法。

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